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  • 标题:Chemical Induction of Focus-Forming Virus from Nonproducer Cells Transformed by Murine Sarcoma Virus
  • 本地全文:下载
  • 作者:Stuart A. Aaronson
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1971
  • 卷号:68
  • 期号:12
  • 页码:3069-3072
  • DOI:10.1073/pnas.68.12.3069
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Focus-forming virus can be induced by chemicals from virus-negative clonal lines of cells transformed by murine sarcoma virus. The viruses activated from such nonproducer cells have the host range and serologic properties of endogenous helper viruses of the cells rather than those of the sarcoma virus used to transform them. The evidence indicates that murine sarcoma virus-transformed nonproducer cells of two species contain the genetic information for both murine sarcoma and helper virus production in an unexpressed form.
  • 关键词:helper virus ; murine leukemia virus ; murine sarcoma virus ; focus-forming units
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