期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：1
页码：15-19
DOI：10.1073/pnas.69.1.15
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：An ATPase activity that is completely dependent on DNA is associated with the ATP-dependent DNase (recB-recC enzyme) purified from Escherichia coli. There is a strong correlation between the ATPase and the DNase activities under various assay conditions. With E. coli DNA as substrate, 8-9 molecules of ATP are hydrolyzed to ADP and inorganic phosphate for every phosphodiester bond hydrolyzed by the DNase. The possible functional relationship of the ATPase and DNase activities is discussed.
关键词：recB-recC enzyme ; E. coli ; ATP to phosphodiester hydrolysis ratio ; DNA-dependent ATPase activity
