期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：2
页码：298-300
DOI：10.1073/pnas.69.2.298
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Low doses of rifampicin, an antibiotic that specifically inhibits RNA polymerase, cure F+ cells from the episome. An E. coli mutant, whose RNA polymerase is resistant to rifampicin, does not show the curing. The growth of Hfr strains, which replicate the chromosome by the F-replication system, is inhibited by low doses of the antibiotic.
