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  • 标题:On the Identity of DOPA Decarboxylase and 5-Hydroxytryptophan Decarboxylase
  • 本地全文:下载
  • 作者:James G. Christenson ; Wallace Dairman ; Sidney Udenfriend
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1972
  • 卷号:69
  • 期号:2
  • 页码:343-347
  • DOI:10.1073/pnas.69.2.343
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Simultaneous immunological titration of DOPA and 5-hydroxytryptophan decarboxylase activities, from a number of tissues of various species, showed that the two activities were not distinguishable with a monospecific antiserum to hog kidney decarboxylase. Together with previous findings, these data firmly establish the concept that in mammalian tissues the two enzyme activities are associated with a single protein, namely aromatic L-amino acid decarboxylase.
  • 关键词:immunological titration ; aromatic L-amino acid decarboxylase ; serotonin ; dopamine ; norepinephrine
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