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  • 标题:Activity of Ribosomes Containing 5S RNA with a Chemically Modified 3′-Terminus
  • 本地全文:下载
  • 作者:S. R. Fahnestock ; M. Nomura
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1972
  • 卷号:69
  • 期号:2
  • 页码:363-365
  • DOI:10.1073/pnas.69.2.363
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Ribosomes containing 5S RNA in which the 3'-terminus has been modified chemically, either by periodate oxidation or by conversion of the terminal ribose to a morpholine derivative, are fully as active in peptidebond formation and polypeptide synthesis as those ribosomes with unmodified 5S RNA. These results exclude models for protein synthesis in which peptidyl-5S RNA is formed as an intermediate.
  • 关键词:B. stearothermophilus ; peptidyl-tRNA ; periodate ; morpholine derivative ; protein synthesis
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