期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1972
卷号:69
期号:6
页码:1569-1573
DOI:10.1073/pnas.69.6.1569
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:A detailed conformational analysis of the known crystal structures of vitamin A, carotenoid, and xanthenoid derivatives has been made. These studies suggest that the visual chromophore 11-cis retinal and its isomers may each occur in several different conformational states, which would be expected to have different lightabsorbing characteristics. The presence of such states for 11-cis retinal and all-trans retinal may contribute to the observed rhodopsin intermediates that have been characterized by different {lambda}max values, and to the breadth of spectral response in scotopic and color vision.