期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：6
页码：1371-1374
DOI：10.1073/pnas.69.6.1371
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Enzymes involved in the expression of the mitochondrial genome in Neurospora crassa are induced by chloramphenicol and ethidium bromide, which block transcription and translation of mitochondrial DNA. It is concluded that most, if not all, proteins of the mitochondrial genetic apparatus are coded by nuclear genes, synthesized on cytoplasmic ribosomes, and controlled by a repressor-like mitochondrial gene product. A model explaining the coordination of nuclear and mitochondrial division cycles by repressor control is discussed.
关键词：chloramphenicol ; ethidium bromide ; repressor control ; model
