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  • 标题:Axonal Sprouts and [3H]Norepinephrine Uptake by Superior Cervical Ganglia in Organ Culture
  • 本地全文:下载
  • 作者:Stephen D. Silberstein ; David G. Johnson ; Ingeborg Hanbauer
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1972
  • 卷号:69
  • 期号:6
  • 页码:1450-1454
  • DOI:10.1073/pnas.69.6.1450
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Superior cervical ganglia from adult rats maintained in organ culture show a progressive increase in the rate of uptake of [3H]norepinephrine. The enhanced uptake of norepinephrine is a consequence of the development of axonal sprouts. Formation of axonal sprouts, which appear to have many of the properties of sympathetic nerve endings, is inhibited by colchicine and vinblastine, presumably because of the interaction of these drugs with neurotubular protein.
  • 关键词:[3H]metaraminol ; colchicine ; vinblastine ; rats
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