期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1972
卷号:69
期号:6
页码:1450-1454
DOI:10.1073/pnas.69.6.1450
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Superior cervical ganglia from adult rats maintained in organ culture show a progressive increase in the rate of uptake of [3H]norepinephrine. The enhanced uptake of norepinephrine is a consequence of the development of axonal sprouts. Formation of axonal sprouts, which appear to have many of the properties of sympathetic nerve endings, is inhibited by colchicine and vinblastine, presumably because of the interaction of these drugs with neurotubular protein.