期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：7
页码：1838-1842
DOI：10.1073/pnas.69.7.1838
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The pattern of elution from a column of Sephadex G-50 of a fucose-labeled carbohydrate component derived from the surface glycoproteins of transformed cells can be altered to resemble that from untransformed cells by enzymatic removal of the sialic acid. These results indicate that the consistent differences found between control and virus-transformed cells may depend upon a relatively specific sialyl transferase that is found in greater amounts (2.5- to 11-times) in transformed cells than in control cells, and in dividing cells as compared to nondividing cells.
