期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：7
页码：1732-1736
DOI：10.1073/pnas.69.7.1732
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：By determination of the rheological flow curve of minute quantities of axoplasm drawn into a microcapillary tube connected to a high vacuum, extruded axoplasm was shown to behave as a pseudoplastic fluid with a viscosity of 106-times that of water and without significant signs of time-dependent thixotropic or viscoelastic properties. A theoretical analysis of peristaltic pumping of such pseudoplastic fluids by sinusoidal surface waves was combined with experimental studies of a mechanical model designed to simulate peristaltic drive. The correlation of the respective data permitted quantitative predictions for the peristaltic mechanism of axonal flow, with speed being a function of peristaltic wave geometry and fluid properties, yielding a theoretical mean value of 0.45 mm/day, i.e., of the same order as that observed in the living nerve fiber.
关键词：neuroplasmic flow ; model ; viscosimetry ; axoplasm
