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  • 标题:Transamidase Reactions Involved in the Enzymic Coagulation of Semen: Isolation of γ-Glutamyl-ε-Lysine Dipeptide from Clotted Secretion Protein of Guinea Pig Seminal Vesicle
  • 本地全文:下载
  • 作者:H. G. Williams-Ashman ; A. C. Notides ; S. S. Pabalan
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1972
  • 卷号:69
  • 期号:8
  • 页码:2322-2325
  • DOI:10.1073/pnas.69.8.2322
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:New supportive evidence is advanced in favor of the hypothesis that the enzymic coagulation of guinea pig semen involves transamidase reactions that result in the formation of {gamma}-glutamyl-{varepsilon}-lysine intermolecular cross linkages between molecules of a basic protein in seminal vesicle secretion. The dipeptide {gamma}-glutamyl-{varepsilon}-lysine was isolated in large quantities from proteolytic digests of the coagulated basic vesicular secretion protein that comprises the seminal clot.
  • 关键词:anterior prostate clotting enzyme ; cross linkages
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