期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：10
页码：2793-2797
DOI：10.1073/pnas.69.10.2793
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：By use of a newly developed procedure for the isolation of mutants with osmotically fragile protoplasts, a mutant of Bacillus subtilis was isolated that has a very active enzyme system for the catabolism of phospholipids via the sequential action of a phospholipase A1 (EC 3.1.1.4 ) and a lysophospholipase (EC 3.1.1.5 ). The wild-type bacteria contain no detectable phospholipase A1 activity, but do contain a protein that specifically inhibits the phospholipase A1 in the mutant. This protein may play an important role in the control of phospholipid catabolism.
