期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1972
卷号：69
期号：10
页码：2950-2953
DOI：10.1073/pnas.69.10.2950
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：We previously proposed that the assembly of tobacco mosaic virus is initiated by disks of 34 protein subunits attaching to the RNA, after which the particle grows by the addition of further disks. Other workers have reported growth from "A-protein" instead. We now report experiments that confirm our previous results and show that the contrary findings are largely due to a nonequilibrium form of A-protein that has a "memory" for the disk state and rapidly reaggregates, either in solution or on the growing particle.
关键词：RNA-protein interactions ; A-protein ; disk state ; subunits
