期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1972
卷号:69
期号:10
页码:2986-2990
DOI:10.1073/pnas.69.10.2986
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Satellite bacteriophage P4 induces a new transcribing enzyme that synthesizes polyriboguanylic acid in the presence of the poly(dG){middle dot}poly(dC) homopolymer pair. This transcribing activity was partially purified and shown to be distinct from the host RNA polymerase. Analysis of conditional lethal mutants suggests that this new enzyme is necessary for replication of phage DNA.
关键词:helper-dependent ; RNA polymerase ; DNA synthesis