期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：3
页码：865-869
DOI：10.1073/pnas.70.3.865
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Using a chemical isotope derivative method, we have determined the minor base composition of the ``70S-associated'' 4S RNA isolated from avian myeloblastosis virus. The minor base composition of this ``70S-associated'' 4S RNA is strikingly similar to that of the corresponding ``free'' 4S RNA of the virion. This minor base content, plus the capacity to esterify amino acids, establishes that both of these virion 4S RNA fractions contain transfer RNA. The percentage of minor bases in virion ``70S-associated'' 4S RNA is, however, much lower than in ``free'' 4S virion RNA and in myeloblast 4S RNA. The implication is that the ``70S-associated'' 4S RNA fraction as isolated herein also contains RNA that is not transfer RNA. This latter RNA may represent either degradation products of high molecular weight RNA or indigenous 4S RNA of undetermined function.
