期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：3
页码：934-938
DOI：10.1073/pnas.70.3.934
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：We have selected from a mixture of random polynucleotides an RNA that is able to replicate in the presence of the DNA-dependent RNA polymerase of Escherichia coli, provided the medium contains Mn2+ and ITP, in addition to ATP, CTP, and UTP. The RNA consists of a chain of about 125 ({+/-} 25) nucleotides and appears to have a defined, nonrepetitive sequence.
