标题：Differentiation of Lens Tissue from the Progeny of Chick Retinal Pigment Cells Cultured In Vitro: A Demonstration of a Switch of Cell Types in Clonal Cell Culture
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1973
卷号：70
期号：5
页码：1495-1499
DOI：10.1073/pnas.70.5.1495
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Clonal cell lines isolated from the pigmented retina of 8.5-day chick embryos initially retained the capacity to form pigment. After several passages, however, many cells lost pigment granules and differentiated into lens-like structures. The lens-specific nature of the structures formed in cultures originally derived from retinal pigment cells was established by both ultrastructural and immunological studies.
