期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1973
卷号:70
期号:7
页码:1950-1954
DOI:10.1073/pnas.70.7.1950
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:In genetic combinations undergoing ribosomal DNA magnification, the frequency of crossing-over between X and Y chromosomes is increased at least 20-fold above that in similar combinations not undergoing magnification. Such recombination occurs at the ribosomal DNA level. The data are consistent with a model where extra copies of ribosomal DNA are formed which, after circularization, are integrated into the chromosome.
关键词:genetic recombination ; frequency of crossing-over ; circularization ; integration