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  • 标题:A Genetic Method for Determining the Order of Events in a Biological Pathway
  • 本地全文:下载
  • 作者:Jonathan Jarvik ; David Botstein
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1973
  • 卷号:70
  • 期号:7
  • 页码:2046-2050
  • DOI:10.1073/pnas.70.7.2046
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:We describe the application of a simple genetic test that indicates the order of events in a morphogenic or biochemical pathway. The test uses temperature-sensitive (ts) and cold-sensitive (cs) mutants, and it orders the times at which the ts and cs defects are expressed.
  • 关键词:cold-sensitive mutants ; temperature-sensitive mutants ; phage P22 ; morphogenesis ; temporal sequence
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