期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1973
卷号:70
期号:7
页码:2139-2144
DOI:10.1073/pnas.70.7.2139
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to homogeneity. The factor, a protein of about 65,000 molecular weight in sodium dodecyl sulfate, discriminates between various mRNAs: it stimulates translation of [α] globin mRNA and of tobacco mosaic virus RNA, but has only a small effect on {beta} globin mRNA and no effect at all on Mengo virus RNA translation.