期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1973
卷号:70
期号:10
页码:2988-2992
DOI:10.1073/pnas.70.10.2988
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the primitive cells of teratocarcinoma. These sera react specifically with the primitive cells and are negative on various types of differentiated teratoma cells derived from the same original tumor. They are negative on all other mouse cells tested, with the exception of male germ cells and cleavage-stage embryos. Thus, teratoma cells possess cell-surface antigens in common with normal cleavage-stage embryos.
关键词:cytotoxic test ; peroxidase-coupled antibody against mouse immunoglobulin ; cell differentiation