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  • 标题:Malignant Transformation of BHK21 Clone 13 Cells by BK Virus—A Human Papovavirus
  • 本地全文:下载
  • 作者:Eugene O. Major ; Giampiero Di Mayorca
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1973
  • 卷号:70
  • 期号:11
  • 页码:3210-3212
  • DOI:10.1073/pnas.70.11.3210
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:BK virus, a widespread human papovavirus, is shown to cause malignant transformation of BHK21 clone 13 cells. The transformed cells grow as tumors upon inoculation in adult hamsters. The question of the possible role of this virus in human neoplasia is raised.
  • 关键词:cell transformation by soft agar assay ; transformed cell tumorigenicity
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