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  • 标题:Magnetic Circular Dichroism Studies XXV. A Preliminary Investigation of Microsomal Cytochromes
  • 本地全文:下载
  • 作者:Peter M. Dolinger ; Michael Kielczewski ; James R. Trudell
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1974
  • 卷号:71
  • 期号:2
  • 页码:399-403
  • DOI:10.1073/pnas.71.2.399
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The application of magnetic circular dichroism as an optical probe for simultaneous identification and determination of at least two microsomal cytochromes is demonstrated. The assignments of the bands in the spectra of microsomal suspensions are made from the spectra of soluble preparations of cytochrome P-450 obtained from Pseudomonas putida and of cytochrome b5 obtained from rat livers.
  • 关键词:hemoproteins ; hepatic microsomes ; drug metabolism ; cytochrome P-450 ; magnetic circular dichroism
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