期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1974
卷号:71
期号:2
页码:399-403
DOI:10.1073/pnas.71.2.399
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:The application of magnetic circular dichroism as an optical probe for simultaneous identification and determination of at least two microsomal cytochromes is demonstrated. The assignments of the bands in the spectra of microsomal suspensions are made from the spectra of soluble preparations of cytochrome P-450 obtained from Pseudomonas putida and of cytochrome b5 obtained from rat livers.
关键词:hemoproteins ; hepatic microsomes ; drug metabolism ; cytochrome P-450 ; magnetic circular dichroism