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  • 标题:The Electrostatic Basis of Mg++ Inhibition of Transmitter Release
  • 本地全文:下载
  • 作者:Robert U. Muller ; Alan Finkelstein
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1974
  • 卷号:71
  • 期号:3
  • 页码:923-926
  • DOI:10.1073/pnas.71.3.923
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The inhibition by Mg++ of stimulus-evoked transmitter release is attributed to a decrease in surface potential, {Psi}0, on the outer surface of the presynaptic terminal and hence a lower surface calcium concentration, [Ca++]0. Data on the frog neuromuscular junction are quantitatively fit by assuming that there is a negative charge density, {sigma
  • 关键词:neuromuscular junction ; quantal content ; diffuse double layer ; Mg++-Ca++ antagonism ; Na+-Ca++ antagonism
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