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  • 标题:Synergistic Interactions of T4 Early Proteins Concerned with Their Binding to DNA
  • 本地全文:下载
  • 作者:Wai Mun Huang ; John M. Buchanan
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1974
  • 卷号:71
  • 期号:6
  • 页码:2226-2230
  • DOI:10.1073/pnas.71.6.2226
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Under appropriate conditions, 19 distinct early proteins produced by bacteriophage T4 bind DNA with various affinities. They include products of genes that have been implicated in T4 DNA metabolism, such as DNA negative, DNA arrest, and DNA delay genes, and others whose roles have not yet been defined. The identifiable DNA-binding proteins are the products of genes 43, rIIA, 46, 30, 39, 52, {beta}gt, 32, and internal protein III. In some cases, protein-protein interactions are involved in the formation of the DNA-protein complexes.
  • 关键词:polyacrylamide gel electrophoresis ; DNA binding proteins ; gene products related to DNA replication ; protein-protein interactions
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