期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1974
卷号:71
期号:6
页码:2273-2275
DOI:10.1073/pnas.71.6.2273
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Apurinic sites disappear from DNA during an incubation of the DNA with the Escherichia coli endonuclease specific for apurinic sites, DNA polymerase I (EC 2.7.7.7 .), and T4 ligase (EC 6.5.1.1 ). Omission of any one of these three enzymes and, in particular, omission of the endonuclease specific for apurinic sites prevents this in vitro repair.
关键词:DNA depurination ; endonuclease specific for apurinic sites ; DNA repair