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  • 标题:A New Transfer RNA Fragment Reaction: TpΨpCpGp Bound to a Ribosome-Messenger RNA Complex Induces the Synthesis of Guanosine Tetra- and Pentaphosphates
  • 本地全文:下载
  • 作者:Dietmar Richter ; Volker A. Erdmann ; Mathias Sprinzl
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1974
  • 卷号:71
  • 期号:8
  • 页码:3226-3229
  • DOI:10.1073/pnas.71.8.3226
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The tetranucleotide Tp{Psi}pCpGp, when bound to Escherichia coli 50S ribosomal subunits, can replace intact tRNA in the stringent factor-directed synthesis of guanosine tetra- and pentaphosphates. The Tp{Psi}pCpGp-dependent fragment reaction has a strict requirement for the 50S and 30S ribosomal subunits and synthetic or natural messenger RNA.
  • 关键词:stringent factor ; puromycin ; 3′-terminus of tRNA ; Escherichia coli
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