期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1974
卷号：71
期号：9
页码：3721-3725
DOI：10.1073/pnas.71.9.3721
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Nucleic acid sequences homologous to a [3H]DNA transcript prepared from an endogenous baboon type C virus are readily detected in both the cellular DNA and RNA of several different Old World monkeys. Competitive radioimmunoassays for the major viral protein (p30) of baboon type C viruses detect viral antigen in a normal stumptail spleen and a rhesus ovarian carcinoma. The p30 antigen from these tissues is closely related by several immunologic criteria to the p30 protein of baboon type C viruses. The results indicate that normal primate tissues transcribe endogenous viral-specific RNA and translate at least one viral structural protein.
关键词：baboon type C virus ; RNA·DNA hybridization ; p30 antigen ; virogene evolution
