期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1974
卷号：71
期号：12
页码：4860-4863
DOI：10.1073/pnas.71.12.4860
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The {sigma} subunit of RNA polymerase from sporulating Bacillus subtilis is markedly inhibited in its ability to direct active transcription of phage {phi}e DNA in vitro. Treatment of sporulating bacteria with chloramphenicol rapidly restores {sigma} activity, suggesting that sporulating cells contain an inhibitor of {sigma} that is physiologically unstable or that becomes unstable after drug treatment. The hypothetical inhibitor is depleted exponentially with an apparent half-life of 11 min at 37{degrees}.
关键词：transcription by phage ϕe ; sigma subunit of RNA polymerase
