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  • 标题:The Presence of I-Region-Associated Antigens on B Cells in Molecules Distinct from Immunoglobulin and H-2K and H-2D
  • 本地全文:下载
  • 作者:Emil R. Unanue ; Martin E. Dorf ; Chella S. David
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1974
  • 卷号:71
  • 期号:12
  • 页码:5014-5016
  • DOI:10.1073/pnas.71.12.5014
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The distribution of I-region-associated antigenic specificities in murine lymphoid cells was studied by immunofluorescence. The antigens were mostly represented in B cells and in macrophages. The complexes of I-anti-I-region-associated antigens were found to be distributed throughout the lymphocyte surface both at 4{degrees} and 37{degrees}. In about two-thirds of the lymphocytes the complexes redistributed into caps after incubation with a second ligand (an anti-mouse immunoglobulin). The I-region specificities were in molecules distinct from immunoglobulin or from the molecules coded by the H-2K and H-2D regions.
  • 关键词:lymphocytes ; histocompatibility antigens ; surface molecules ; immunogenetics
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