期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1975
卷号:72
期号:4
页码:1268-1271
DOI:10.1073/pnas.72.4.1268
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Through the use of specific immunoadsorbent columns, it is shown that Escherichia coli aspartokinase I-homoserine dehydrogenase I, aspartokinase II-homoserine dehydrogenase II, aspartokinase III, and homoserine kinase, enzymes involved in the same complex biosynthetic pathway, share antigenic determinants. This raises the question of a common origin for the four cibtenoirart kinases. (Aspartate kinase or ATP:L aspartate 4-phosphotransferase, EC 2.7.2.4 ; homoserine dehydrogenase or Lhomoserine:NADP oxidoreductase, EC 1.1.1.3 ; homoserine kinase or ATP:L-homoserine O-phosphotransferase, EC 2.7.1.39 .)