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  • 标题:Evolution of biosynthetic pathways: immunological approach
  • 本地全文:下载
  • 作者:P Truffa-Bachi ; N Guiso ; G N Cohen
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1975
  • 卷号:72
  • 期号:4
  • 页码:1268-1271
  • DOI:10.1073/pnas.72.4.1268
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Through the use of specific immunoadsorbent columns, it is shown that Escherichia coli aspartokinase I-homoserine dehydrogenase I, aspartokinase II-homoserine dehydrogenase II, aspartokinase III, and homoserine kinase, enzymes involved in the same complex biosynthetic pathway, share antigenic determinants. This raises the question of a common origin for the four cibtenoirart kinases. (Aspartate kinase or ATP:L aspartate 4-phosphotransferase, EC 2.7.2.4 ; homoserine dehydrogenase or Lhomoserine:NADP oxidoreductase, EC 1.1.1.3 ; homoserine kinase or ATP:L-homoserine O-phosphotransferase, EC 2.7.1.39 .)
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