期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1975
卷号：72
期号：6
页码：2451-2455
DOI：10.1073/pnas.72.6.2451
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Actin has been shown to be present in the nucleoli, kinetochore and centriolar regions, and in the mitotic spindle of rat kangaroo cells which have been stained with fluorescently labeled heavy meromyosin. The actin in the spindle is confined to the fibers that connect the chromosomes with the centriolar region. Actin was not present in astral fibers, in the continuous spindle fibers that connect the poles, or in non-kinetochore regions of the chromosomes. The specific localization of actin in chromosomal spindle fibers suggests an actin-mvosin interaction as the force-producing mechanism for chromosomal movement.
