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  • 标题:Release of (oligo) peptidyl-tRNA from ribosomes by erythromycin A
  • 本地全文:下载
  • 作者:T Otaka ; A Kaji
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1975
  • 卷号:72
  • 期号:7
  • 页码:2649-2652
  • DOI:10.1073/pnas.72.7.2649
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Erythromycin A released peptidyl-tRNA in the in vitro polypeptide synthesis system with bacterial components programmed by synthetic polynucleotide. This is consistent with our hypothesis that erythromycin A inhibits translocation by preventing proper situation of oligopeptidyl-tRNA in the donor (D) site on ribosomes.
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