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  • 标题:Cleavage of adenovirus messenger RNA and of 28S and 18S ribosomal RNA by RNase III
  • 本地全文:下载
  • 作者:H Westphal ; R J Crouch
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1975
  • 卷号:72
  • 期号:8
  • 页码:3077-3081
  • DOI:10.1073/pnas.72.8.3077
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Escherichia coli ribonuclease III cleaves adenovirus messenger RNA and mammalian 28S and 18S ribosomal RNA. Fragmentation is not random, but in each case a specific collection of products is generated. This points to the potential use of the enzyme as a tool for specific fragmentation of RNA. Cleavage by RNase III abolishes the capability of adenovirus messenger RNA to direct cell-free synthesis of virus polypeptides.
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