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  • 标题:5'-terminal structure of poliovirus polyribosomal RNA is pUp
  • 本地全文:下载
  • 作者:M J Hewlett ; J K Rose ; D Baltimore
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:2
  • 页码:327-330
  • DOI:10.1073/pnas.73.2.327
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Poliovirus RNA purified from virus-specific polyribosomes does not contain m7G in a 5'-5'-pyrophosphate linkage at its 5'-end. The only potential 5'-end found in ribonuclease digests of this RNA is pUp, which is present in a yield of 1 mole/mole of poliovirus RNA. We conclude that a 5'-terminal m7G is not required for translation of at least one RNA species in animal cells.
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