期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1976
卷号：73
期号：4
页码：1288-1292
DOI：10.1073/pnas.73.4.1288
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Antiserum to a glycoprotein antigen complex of 23,000 and 30,000 dalton subunits (p23,30), isolated and purified from a human lymphoblastoid B cell line, was shown to be highly specific for human bursal-equivalent-processed (B) cells, reactive with 15-20% of human Null cells, but completely unreactive with human thymus-processed (T) cells. The p23,30 antigen is widely distributed on chronic lymphatic leukemic cells, 85% of acute lymphatic leukemic cells, all acute myelogenous leukemic cells, but not on chronic myelogenous leukemic cells. A rabbit antiserum specific for normal human thymocytes has also been prepared; it is reactive only with precisely that subset of acute lymphatic leukemic cells (15%) whose members do not have p23,30 on their surfaces.
