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  • 标题:Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes
  • 本地全文:下载
  • 作者:L Orci ; D Baetens ; C Rufener
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:4
  • 页码:1338-1342
  • DOI:10.1073/pnas.73.4.1338
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Insulin-, glucagon-, and somatostatin-contianing cells, identified by immunofluorescent staining, were quantitated morphometrically in sections of pancreas obtained from diabetic and nondiabetic humans and rats. Both the volume density and number of somatostatin- and glucagon-containing cells were significantly increased in the islets of juvenile-type human diabetics and of streptozotocin diabetic rats.
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