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  • 标题:Characterization of a gamma-carboxyglutamic acid-containing protein from bone
  • 本地全文:下载
  • 作者:P A Price ; A A Otsuka ; J W Poser
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:5
  • 页码:1447-1451
  • DOI:10.1073/pnas.73.5.1447
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:A gamma-carboxyglutamic acid-containing protein has been purified from the calcified tissues of several vertebrates. The presence of three-gamma-carboxyglutamic acid residues in the bovine protein was established by alkaline hydrolysis and amino acid analysis, a method based upon studies with synthetic gamma-carboxyglutamic acid. The identity of gamma-carboxyglutamic acid in the bovine protein was established by mass spectroscopy on the unknown amino acid isolated from alkaline hydrolysates.
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