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  • 标题:Linking numbers and nucleosomes
  • 本地全文:下载
  • 作者:F H Crick
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:8
  • 页码:2639-2643
  • DOI:10.1073/pnas.73.8.2639
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:In considering supercoils formed by closed double-stranded molecules of DNA certain mathematical concepts, such as the linking number and the twist, are needed. The meaning of these for a closed ribbon is explained and also that of the writhing number of a closed curve. Some simple examples are given, some of which may be relevant to the structure of chromatin.
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