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  • 标题:Inhibition of erythrocyte phosphate transport by high pressures
  • 本地全文:下载
  • 作者:R B Murphy ; W F Libby
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:8
  • 页码:2767-2769
  • DOI:10.1073/pnas.73.8.2767
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Pressures of 200-1000 atmospheres (20-100 MPa) are found to decrease significantly the amount of phosphate (H32PO4-2)transported into the rabbit erythrocyte under otherwise physiological conditions. Such compression does not cause irreversible morphological changes or result in membrane disruption. The findings are interpreted in terms of a lipid phase transition induced by the high pressure, which is propagated to the associated phosphate transport system by a physical mechanism.
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