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  • 标题:Influenza virus genome consists of eight distinct RNA species
  • 本地全文:下载
  • 作者:D McGeoch ; P Fellner ; C Newton
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:9
  • 页码:3045-3049
  • DOI:10.1073/pnas.73.9.3045
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The genomic RNA of the avian influenza A virus, fowl plague, was fractionated into eight species by electrophoresis in polyacrylamide-agarose gels containing 6 M urea. The separated 32P-labeled RNA species were characterized by digestion with RNase T1 and fractionation of the resulting oligonucleotides by two-dimensional gel electrophoresis; this demonstrated that each species has a distinct nucleotide sequence. A tentative correlation of each genome RNA species with the virus protein that it encodes was made.
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