期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1976
卷号:73
期号:10
页码:3484-3487
DOI:10.1073/pnas.73.10.3484
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Examination of old human lenses indicates that low-molecular-weight alpha crystallin is not present in the inner 30-40%, the nucleus, of the lens. The remainder of such lenses, the periphery, contains normal levels of this protein. This finding is in marked contrast to observations in young lenses, where a large quantity of this protein is found throughout the tissue.