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  • 标题:On the specificity of synapse formation
  • 本地全文:下载
  • 作者:D G Puro ; M Nirenberg
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1976
  • 卷号:73
  • 期号:10
  • 页码:3544-3548
  • DOI:10.1073/pnas.73.10.3544
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Clonal neuroblastome X glioma hybrid cells form synapses with striated muscle cells from different muscles and from different organisms, such as chick, mouse, and rat. Under appropriate conditions 65-80% of the muscle cells exhibited synaptic responses. The results indicate that most striated muscle cells have the same specificity for synapse formation and suggest that synaptogenesis is not dependent on interactions between complementary molecules on neuron and muscle cells that code for different synaptic connections.
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