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  • 标题:Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide
  • 本地全文:下载
  • 作者:A L Goldstein ; T L Low ; M McAdoo
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1977
  • 卷号:74
  • 期号:2
  • 页码:725-729
  • DOI:10.1073/pnas.74.2.725
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The amino acid sequence of a biologically active polypeptide isolated from calf thymus, termed thymosin alpha1, has been determined. Thymosin alpha1 is a heat stable, highly acidic molecule composed of 28 amino acid residues. This peptide is one of several present in thymosin fraction 5 that may participate in the regulation, differentiation and function of thymus-dependent lymphocytes (T cells). A nomenclature for the family of polypeptides present in thymosin fraction 5 is suggested.
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