期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1977
卷号：74
期号：9
页码：3898-3902
DOI：10.1073/pnas.74.9.3898
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The presence and accumulation in murine erythroleukemic cells transformed by Friend virus of the erythrocyte membrane-associated protein spectrin has been investigated. Spectrin was present in the uninduced cells and was induced 10- to 20-fold in dimethyl sulfoxide-treated differentiating cells. The intracellular concentration of spectrin reached a peak on the third day of dimethyl sulfoxide treatment, after which it fell to levels found in mouse erythrocytes. We also found that the small subunit of spectrin was phosphorylated in the cells.
