期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1977
卷号：74
期号：9
页码：3947-3950
DOI：10.1073/pnas.74.9.3947
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Several newly isolated temperature-sensitive dnaE mutants of Escherichia coli exhibit powerful mutagenic action at permissive temperatures. Mutation rates for the two most active mutants were assayed at four different temperatures and compared to wild-type behavior. Temperature-resistant revertants of the original temperature-sensitive dnaE mutants exhibited lower, nearly normal, mutation rates, but no antimutator strains were found.
