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  • 标题:Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex
  • 本地全文:下载
  • 作者:J Silver ; W A Russell ; B L Reis
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1977
  • 卷号:74
  • 期号:11
  • 页码:5131-5134
  • DOI:10.1073/pnas.74.11.5131
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Alloantisera directed against the alloantigens determined by the I-E and I-C subregions of the murine major histocompatibility complex precipitate two components that have molecular weights of 35,000 and 29,000. These components, when analyzed by partial NH2-terminal sequencing, show no homology to two components of similar size determined by the I-A subregion. However, the large chain determined by the murine I-E and/or I-C subregion is homologous to the large chain of the human HLA-D region alloantigen, although the small chains isolated from these two species do not display any such homology.
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