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  • 标题:Antibody response of mice to chemically induced tumors
  • 本地全文:下载
  • 作者:J P Brown ; J M Klitzman ; I Hellström
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1978
  • 卷号:75
  • 期号:2
  • 页码:955-958
  • DOI:10.1073/pnas.75.2.955
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:BALB/c mice immunized with syngeneic methylcholanthrene-induced fibrosarcomas did not have antibodies against the unique tumor-specific transplantation antigens, even though they were capable of rejecting a lethal dose of tumor cells. Endogenous murine leukemia virus antigens expressed by certain of the tumors did, however, elicit high titers of antibodies, accounting for serological crossreactions that occurred between those tumors.
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