标题：Regulation of cholesterol biosynthesis in HeLa S3G cells by serum lipoproteins: Dexamethasone-mediated interference with suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1978
卷号：75
期号：5
页码：2103-2107
DOI：10.1073/pnas.75.5.2103
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Depression of the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase [mevalonate:NADP+ oxidoreductase (CoA-acylating); EC 1.1.1.34 ] was elicited by the removal of serum from the growth medium of HeLa S3G cells with a concomitant expected increase in cellular sterol biosynthesis; if dexamethasone (9-fluoro-11{beta
