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  • 标题:Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy
  • 本地全文:下载
  • 作者:Lorena Diéguez ; David Caballero ; Josep Calderer
  • 期刊名称:Biosensors
  • 电子版ISSN:2079-6374
  • 出版年度:2012
  • 卷号:2
  • 期号:2
  • 页码:114-126
  • 出版社:MDPI Publishing
  • 摘要:Abstract: New silicon nitride coated optical gratings were tested by means of Optical Waveguide Lightmode Spectroscopy (OWLS). A thin layer of 10 nm of transparent silicon nitride was deposited on commercial optical gratings by means of sputtering. The quality of the layer was tested by x-ray photoelectron spectroscopy and atomic force microscopy. As a proof of concept, the sensors were successfully tested with OWLS by monitoring the concentration dependence on the detection of an antibody-protein pair. The potential of the Si3N4 as functional layer in a real-time biosensor opens new ways for the integration of optical waveguides with microelectronics.
  • 关键词:silicon nitride; optical gratings; waveguide; biosensor
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